Antibacterial activity of two phloroglucinols, flavaspidic acids AB and PB, from Dryopteris crassirhizoma
Identifieur interne : 001C29 ( Main/Exploration ); précédent : 001C28; suivant : 001C30Antibacterial activity of two phloroglucinols, flavaspidic acids AB and PB, from Dryopteris crassirhizoma
Auteurs : Hyang Burm Lee [Corée du Sud] ; Jin Cheol Kim [Corée du Sud] ; Sang Myung Lee [Corée du Sud]Source :
- Archives of Pharmacal Research [ 0253-6269 ] ; 2009-05-01.
English descriptors
Abstract
Abstract: The antimicrobial effect of solvent extracts from the rhizome of a thick-stemmed wood fern (Dryopteris crassirhizoma) was evaluated and its phloroglucinol components, flavaspidic acids PB and AB. Flavaspidic acids PB and AB were isolated from the D. crassirhizoma rhizomes by methanol extraction, followed by silica gel and Sephadex LH-20 column chromatography. The chemical structures were characterized by spectral techniques, including ESI-MS, UV, 1H- and 13C-NMR spectrum analysis. When the antimicrobial activity of the extracts and compounds was tested by the paper disc method, the extracts and compounds were highly active against Gram-positive bacteria, such as methicillin-resistant Staphylococcus aureus KCTC 1928 (a MRSA bacterium), Streptococcus mutans and Bacillus subtilis. The extracts and compounds were not active against fungi and chlorella. Our study revealed that the antibacterial activity of samples from D. crassirhizoma was mainly related to the flavaspidic acids.
Url:
DOI: 10.1007/s12272-009-1502-9
Affiliations:
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Res.</title><idno type="ISSN">0253-6269</idno><idno type="eISSN">1976-3786</idno><imprint><publisher>Pharmaceutical Society of Korea</publisher><pubPlace>Heidelberg</pubPlace><date type="published" when="2009-05-01">2009-05-01</date><biblScope unit="volume">32</biblScope><biblScope unit="issue">5</biblScope><biblScope unit="page" from="655">655</biblScope><biblScope unit="page" to="659">659</biblScope></imprint><idno type="ISSN">0253-6269</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0253-6269</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antibacterial activity</term><term>Dryopteris crassirhizoma</term><term>Flavaspidic acids</term><term>Phloroglucinols</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: The antimicrobial effect of solvent extracts from the rhizome of a thick-stemmed wood fern (Dryopteris crassirhizoma) was evaluated and its phloroglucinol components, flavaspidic acids PB and AB. Flavaspidic acids PB and AB were isolated from the D. crassirhizoma rhizomes by methanol extraction, followed by silica gel and Sephadex LH-20 column chromatography. The chemical structures were characterized by spectral techniques, including ESI-MS, UV, 1H- and 13C-NMR spectrum analysis. When the antimicrobial activity of the extracts and compounds was tested by the paper disc method, the extracts and compounds were highly active against Gram-positive bacteria, such as methicillin-resistant Staphylococcus aureus KCTC 1928 (a MRSA bacterium), Streptococcus mutans and Bacillus subtilis. The extracts and compounds were not active against fungi and chlorella. Our study revealed that the antibacterial activity of samples from D. crassirhizoma was mainly related to the flavaspidic acids.</div></front></TEI><affiliations><list><country><li>Corée du Sud</li></country></list><tree><country name="Corée du Sud"><noRegion><name sortKey="Lee, Hyang Burm" sort="Lee, Hyang Burm" uniqKey="Lee H" first="Hyang Burm" last="Lee">Hyang Burm Lee</name></noRegion><name sortKey="Kim, Jin Cheol" sort="Kim, Jin Cheol" uniqKey="Kim J" first="Jin Cheol" last="Kim">Jin Cheol Kim</name><name sortKey="Lee, Hyang Burm" sort="Lee, Hyang Burm" uniqKey="Lee H" first="Hyang Burm" last="Lee">Hyang Burm Lee</name><name sortKey="Lee, Sang Myung" sort="Lee, Sang Myung" uniqKey="Lee S" first="Sang Myung" last="Lee">Sang Myung Lee</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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